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nkb senktide  (Cayman Chemical)


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    Cayman Chemical nkb senktide
    Nkb Senktide, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nkb+senktide/pm40466945-80-12-14?v=Cayman+Chemical
    Average 90 stars, based on 1 article reviews
    nkb senktide - by Bioz Stars, 2026-08
    90/100 stars

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    LH responses (mean ± SEM) in chronically catheterized GD85 lamb fetuses given IV bolus injections of (A) saline (S, 500 µL); (B) mouse kisspeptin-10 (K, 10 µg); <t>Senktide</t> (Sk, 50 µg), and GnRH (G; 50 µg) at time 0. Fetuses were fitted with indwelling jugular vein and carotid artery catheters on GD82 for drug infusion and blood collection, respectively. Chronic experiments were performed on unanesthetized fetuses between GD85 and GD89. Data were analyzed by 2-way ANOVA (sex × time) for repeated measures followed by Bonferroni’s multiple comparison tests. When there was a significant interaction between sex and time, the time effect was evaluated individually for each sex using a 1-way ANOVA for repeated measures. *P < .05 vs time = –30 minutes. †P < .05 male vs female.
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    LH responses (mean ± SEM) in chronically catheterized GD85 lamb fetuses given IV bolus injections of (A) saline (S, 500 µL); (B) mouse kisspeptin-10 (K, 10 µg); <t>Senktide</t> (Sk, 50 µg), and GnRH (G; 50 µg) at time 0. Fetuses were fitted with indwelling jugular vein and carotid artery catheters on GD82 for drug infusion and blood collection, respectively. Chronic experiments were performed on unanesthetized fetuses between GD85 and GD89. Data were analyzed by 2-way ANOVA (sex × time) for repeated measures followed by Bonferroni’s multiple comparison tests. When there was a significant interaction between sex and time, the time effect was evaluated individually for each sex using a 1-way ANOVA for repeated measures. *P < .05 vs time = –30 minutes. †P < .05 male vs female.
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    LH responses (mean ± SEM) in chronically catheterized GD85 lamb fetuses given IV bolus injections of (A) saline (S, 500 µL); (B) mouse kisspeptin-10 (K, 10 µg); Senktide (Sk, 50 µg), and GnRH (G; 50 µg) at time 0. Fetuses were fitted with indwelling jugular vein and carotid artery catheters on GD82 for drug infusion and blood collection, respectively. Chronic experiments were performed on unanesthetized fetuses between GD85 and GD89. Data were analyzed by 2-way ANOVA (sex × time) for repeated measures followed by Bonferroni’s multiple comparison tests. When there was a significant interaction between sex and time, the time effect was evaluated individually for each sex using a 1-way ANOVA for repeated measures. *P < .05 vs time = –30 minutes. †P < .05 male vs female.

    Journal: Endocrinology

    Article Title: Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep

    doi: 10.1210/endocr/bqaa013

    Figure Lengend Snippet: LH responses (mean ± SEM) in chronically catheterized GD85 lamb fetuses given IV bolus injections of (A) saline (S, 500 µL); (B) mouse kisspeptin-10 (K, 10 µg); Senktide (Sk, 50 µg), and GnRH (G; 50 µg) at time 0. Fetuses were fitted with indwelling jugular vein and carotid artery catheters on GD82 for drug infusion and blood collection, respectively. Chronic experiments were performed on unanesthetized fetuses between GD85 and GD89. Data were analyzed by 2-way ANOVA (sex × time) for repeated measures followed by Bonferroni’s multiple comparison tests. When there was a significant interaction between sex and time, the time effect was evaluated individually for each sex using a 1-way ANOVA for repeated measures. *P < .05 vs time = –30 minutes. †P < .05 male vs female.

    Article Snippet: The NKB agonist senktide was purchased from Tocris (Minneapolis, MN).

    Techniques: Saline, Comparison

    Fluorescent in situ hybridization (FISH) detection of kisspeptin (KISS1), neurokinin B/tachykinin3 (TAC3) and prodynorphin (PDYN) mRNA. (A) Confocal image (X60 magnification) showing representative cells in the ARC of a GD86 fetus expressing kisspeptin (white), NKB (green), and Dyn (red). Section was counterstained using DAPI (blue) for visualization of cell nuclei. (B) Higher magnification view of cell identified in the square in A. Scale bar = 25 μm (A) and 10 μm (B).

    Journal: Endocrinology

    Article Title: Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal Sheep

    doi: 10.1210/endocr/bqaa013

    Figure Lengend Snippet: Fluorescent in situ hybridization (FISH) detection of kisspeptin (KISS1), neurokinin B/tachykinin3 (TAC3) and prodynorphin (PDYN) mRNA. (A) Confocal image (X60 magnification) showing representative cells in the ARC of a GD86 fetus expressing kisspeptin (white), NKB (green), and Dyn (red). Section was counterstained using DAPI (blue) for visualization of cell nuclei. (B) Higher magnification view of cell identified in the square in A. Scale bar = 25 μm (A) and 10 μm (B).

    Article Snippet: The NKB agonist senktide was purchased from Tocris (Minneapolis, MN).

    Techniques: In Situ Hybridization, Expressing